Ghana is amongst Africa's top five seeds for the final qualifying for the 2014 World Cup but Tunisia take the place of the disqualified Cape Verde.
The Black Stars and four other group winners from the second round qualifiers, Ivory Coast, Algeria and Nigeria and Tunisia based on the FIFA ranking following Cape Verde's disqualification for fielding an ineligible player.
Tunisia whom Cape Verde fielded an eligible player against in their Group B campaign thus qualify for the final round.
All five teams will avoid each other in the draw for Africa's third round qualifying.
The Confederation of African Football -CAF, announced the seeding on Thursday.
Ghana can draw either Egypt, Burkina Faso, Ethiopia, Senegal or Cameroon for the two-leg ties, with the winners going to the finals in Brazil.
With the seeding revealed following Thursday's release of the FIFA World ranking, all is set for the final round draw which will take place in Cairo on 16 September to determine the pairings.